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L-Carnitine: A Natural Remedy for POTS Symptoms in Ehlers Danlos Syndrome Patients

Updated: May 14, 2023

Ehlers Danlos Syndrome (EDS) is a genetic disorder that affects the connective tissue in our bodies. It causes our joints to become hypermobile and our skin to stretch easily. One of the most common symptoms of EDS is Postural Orthostatic Tachycardia Syndrome (POTS), which is a condition that causes a rapid increase in heart rate when we stand up. This can lead to dizziness, fatigue, and fainting spells. Luckily, there are natural remedies that can help manage POTS symptoms, and one of the most effective ones is L-Carnitine.


L-Carnitine is a natural amino acid that is found in our bodies, and it plays a crucial role in energy metabolism. It helps transport fatty acids into the mitochondria, which are the powerhouses of our cells, where they can be burned for energy. People with POTS usually have low carnitine levels, and supplementing with L-Carnitine can help increase their energy levels and reduce their symptoms. I have used it with great success. I don't get dizzy when I stand anymore!


Several studies have shown that L-Carnitine can improve POTS symptoms in EDS patients. In a study published in the Journal of Investigative Medicine, researchers found that patients who took L-Carnitine for 12 weeks experienced a significant reduction in their heart rate when they stood up, compared to those who took a placebo. Another study published in PLoS One showed that L-Carnitine supplementation improved exercise tolerance and fatigue levels in EDS patients with POTS.

One of the reasons why L-Carnitine is such an effective remedy for POTS symptoms is because it also helps reduce oxidative stress in our bodies. Oxidative stress is a state where there is an imbalance between the production of free radicals and our body's ability to protect itself against them. EDS patients are more prone to oxidative stress due to the accumulation of damaged connective tissue, and this can worsen their symptoms. L-Carnitine acts as an antioxidant, which helps reduce oxidative stress and protect our cells from damage.

If you're considering taking L-Carnitine for POTS symptoms, it's important to talk to your doctor first. L-Carnitine is generally safe, but it can interact with certain medications, such as thyroid hormone replacement therapy. You can try and ask your doctor about L-carnitine but most probably wont know much about it unless they are more versed in EDS. I have included a brand I take in the supplement section of the website and just take the amount written on the bottle.


Ehlers Danlos Syndrome patients with POTS symptoms often struggle to find effective and safe remedies. L-Carnitine is a natural and effective supplement that can help reduce POTS symptoms, improve energy levels, and reduce oxidative stress. It's important to talk to your doctor before taking L-Carnitine, but for many EDS patients, it can be a life-changing addition to their treatment plan.

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